Institute of Physiology - Publications

Skeletal Muscle Uncoupling Proteins in Mice Models of Obesity

By Institute of Physiology on 24. 03. 2022
Authors: Lidija Križančić Bombek, Maša Čater
Journal: Metabolites
https://doi.org/10.3390/metabo12030259

Obesity and accompanying type 2 diabetes are among major and increasing worldwide problems that occur fundamentally due to excessive energy intake during its expenditure. Endotherms continuously consume a certain amount of energy to maintain core body...

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Mechanisms of Post-Pancreatitis Diabetes Mellitus and Cystic Fibrosis-Related Diabetes: A Review of Preclinical Studies

By Institute of Physiology on 25. 10. 2021
Authors: Eleonora Gal, Jurij Dolenšek, Andraž Stožer, Laszlo Czako, Attila Ebert, Viktoria Venglovecz
Journal: Frontiers in Endocrinology
https://doi.org/10.3389/fendo.2021.715043

Anatomical proximity and functional correlations between the exocrine and endocrine pancreas warrant reciprocal effects between the two parts. Inflammatory diseases of the exocrine pancreas, such as acute or chronic pancreatitis, or the presence of cystic fibrosis disrupt endocrine function,...

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In Vitro Culturing of Adult Stem Cells: The Importance of Serum and Atmospheric Oxygen

By Institute of Physiology on 27. 08. 2021
Authors: Maša Čater, Gregor Majdič
Journal: Advances in experimental medicine and biology
https://doi.org/10.1007/5584_2021_656

Adult stem cells are undifferentiated cells found in many different tissues in the adult human and animal body and are thought to be important for replacing damaged and dead cells during life. Due to their differentiation abilities, they have significant potential for regeneration and...

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Glucose-dependent activation, activity, and deactivation of beta cell networks in acute mouse pancreas tissue slices

By Institute of Physiology on 21. 07. 2021
Authors: Andraž Stožer, Maša Skelin Klemen, Marko Gosak, Lidija Križančić Bombek, Viljem Pohorec, Marjan Slak Rupnik, Jurij Dolenšek
Journal: American Journal of Physiology - Endocrinology and Metabolism
https://doi.org/10.1152/ajpendo.00043.2021

Many details of glucose-stimulated intracellular calcium changes in beta cells during activation, activity, and deactivation, as well as their concentration-dependence, remain to be analyzed. Classical physiological experiments indicated that in islets, functional differences between...

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